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Macrophages

By Jennifer Moll, About.com

Updated: September 25, 2008

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

Definition: Macrophages are cells of the immune system that exist in tissues and help defend the body against foreign cells like bacteria. They can release chemicals that stimulate other cells of the immune system, in addition to ingesting damaged and foreign cells.

Macrophages often migrate to inflamed areas of the body, including areas of inflammation on the vessels of the cardiovascular system. The presence of these macrophages, in addition to high cholesterol and triglycerides, can cause the formation of atherosclerosis.

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