1. Health
You can opt-out at any time. Please refer to our privacy policy for contact information.



Updated September 25, 2008

Definition: Rhabdomyolysis is a rare, but serious, medical condition in which skeletal muscle fibers rapidly breakdown and release proteins, such as creatine phosphokinase and myoglobin, into the bloodstream. It is characterized by profound muscle weakness and tenderness, brown-colored urine, and a creatine phosphokinase level that measures more than 10 times the upper allowable limit (in this case, 150 IU/L).

This condition could lead to kidney failure, arrthymias, and death if not treated quickly.

©2014 About.com. All rights reserved.

We comply with the HONcode standard
for trustworthy health
information: verify here.