From Jennifer Moll,
Your Guide to Cholesterol.
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About.com Health's Disease and Condition content is reviewed by Rich Fogoros, MD

Triglycerides are a type of fat, or lipid, that accounts for the majority of fat in our diets. Triglycerides are important because they provide the body the energy it needs to function on a daily basis. If you have an excess of triglycerides in the body, they will be stored as fat.

Triglycerides are either made in the liver or consumed in the diet and then absorbed into the body through the small intestine. Additionally, triglycerides never travel to their destination in the body alone; they attach to a protein and become a lipoprotein referred to as a chylomicron or a very low-density lipoprotein (VLDL). These lipoproteins are not very dense, or heavy. Therefore, along with low-density lipoproteins (LDL), they run the risk of potentially contributing to heart disease.

What should my triglyceride levels be?

Elevated levels of triglycerides are also a risk factor for heart disease. According to the National Heart, Lung, and Blood Institute:

• Triglyceride levels should be below 150 mg/dL (1.69 mmol/L).
• Levels between 150 mg/dL (1.69 mmol/L ) and 199 mg/dL (2.25 mmol/L) are considered borderline high.
• Levels between 200-499 mg/dL (2.26-5.63 mmol/L) are considered high.
• Levels above 500 mg/dL (5.64 mmol/L) or considered extremely high.

Who Is At Risk For Acquiring High Triglyceride Levels?

There are primary and secondary causes of hypertriglyceridemia, or high triglyceride levels. Primary causes include various genetic disorders that affect the metabolism of triglycerides and/or cholesterol. Secondary causes are usually due either excessive fat in the diet or an underlying conditions that would include:

• Diabetes
• Metabolic Syndrome
• Obesity
• Hypothyroidism
• Excessive Alcohol Consumption
• Nephrotic Syndrome

If any of these risk factors are present, your health care provider will probably recommend that you have a lipid panel performed more frequently (every one or two years as opposed to five years).

What Can Happen If My Triglyceride Levels Are Too High?

Having high triglyceride levels may place you at risk for coronary heart disease. However, this fact has not been exclusively proven. When triglyceride levels are high, most often, LDL levels will be high as well. Elevated LDL levels are an important risk factor for heart disease. However, it has not been fully established that high triglyceride levels alone are capable of producing health disease. While there are some studies that have stated that high triglycerides alone are not an independent risk factor for heart disease, there have been other studies that have indicated that triglycerides alone, even with normal LDL and HDL levels, may cause the development of coronary heart disease.

How Are High Triglyceride Levels Treated?

Even though the verdict is still out on whether or not high triglyceride levels alone can cause heart disease, it is still important to restore them back to their normal levels. High triglyceride levels are initially treated with a low-fat, low-carbohydrate diet and lifestyle modifications. When this does not work, your health care provider may want to add medication to help lower your triglyceride levels.

<sub>Sources
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (PDF)

Heart Protection Study Collaborative Group. MRC/BHF heart protection study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomized placebo-controlled trial. Lancet 2002;360:7-22.

Pejic RN, Lee DT. Hypertriglyceridemia. J Am Board Fam Med. 2006;19(3):310-316.</sub>