An occlusion of an artery in the heart or in another area of the body may be caused by the buildup of atherosclerotic plaque, by plaque that has broken off from one area of a vessel and traveled to another part of the body, or by a blood clot. Partial occlusions limit, but do not completely block, blood flow. On the other hand, complete occlusions completely restrict blood flow.
Occlusions prevent organs and tissues from obtaining the oxygen and nutrients they need to survive. This, in turn, causes tissue death and serious conditions, such as a heart attack or stroke.

