Its true that this combination can greatly improve all aspects of your lipid profile. Most other cholesterol-lowering agents on the market can impact all aspects of your cholesterol, however niacin is the only product on the market that can have the most impact on your HDL, or good cholesterol. However, if dosed too high, taking niacin with cholesterol-lowering drugs, such as statins or fibrates may produce some serious side effects such as myopathies and elevated liver enzymes.
Additionally, while adding niacin can help improve your lipid profile, it could also worsen certain medical conditions, including:
- blood sugar control in diabetics
- gout
- peptic ulcer disease
Many healthcare providers are open to discussing with you your options for lowering cholesterol, and niacin is often included among those options. Talk to your healthcare provider regarding your desire to add niacin to your cholesterol-lowering regimen in order to avoid potential problems down the road.
Sources:
Third Report of the National Cholesterol Education Program
(NCEP) Expert Panel on Detection, Evaluation, and Treatment of
High Blood Cholesterol in Adults (PDF), July 2004, The National Institutes of Heath: The National Heart, Lung, and Blood Institute.

